Cinnamic acids and derivatives
Cayman Chemical p-CoumarIc AcId 50g
A hydroxy derivative of cinnamic acid that can be found in a variety of edible plants that is reported to have antioxidant, anti-inflammatory, and antimicrobial activity
Cayman Chemical FerulIc AcId 5g
A phenol with diverse biological activities; active against the yeast S. cerevisiae at 250 ppm and the bacteria E. coli, S. aureus, and B. cereus at 500 UG/ml; dietary administration reduces serum total cholesterol levels in a rat model of diet-induced hypercholesterolemia at 0.2% w/w; suppresses benzo(a)pyrene-induced forestomach tumor formation in mice
Medchemexpress LLC Tyrphostin A1 | 2826-26-8 | 99.0% | 184.19 | 25 MG
Tyrphostin A1 (AG9) is a compound that inhibits CD40L-stimulated IL-12 production and antigen-induced generation of Th1 cells. It blocks CD40L-induced translocation of NF-κB to the nucleus, reducing IL-12 p40 gene activation. In vivo, it decreases the generation of myelin basic protein (MBP) specific encephalitogenic T cells and attenuates experimental allergic encephalomyelitis (EAE).
- Inhibits CD40L-stimulated IL-12 production in macrophage cultures
- Inhibits antigen-induced generation of Th1 cells
- Blocks CD40L-induced translocation of NF-κB to the nucleus
- Reduces activation of the IL-12 p40 gene
- Decreases generation of myelin basic protein (MBP) specific encephalitogenic T cells
- Attenuates experimental allergic encephalomyelitis (EAE)
- Differentiates TK-mediated effects from non-specific effects due to weak TK inhibition (IC50>1250 μM for epidermal growth factor receptor (EGFR) kinase)
Cayman Chemical FerulIc AcId 50g
A phenol with diverse biological activities; active against the yeast S. cerevisiae at 250 ppm and the bacteria E. coli, S. aureus, and B. cereus at 500 UG/ml; dietary administration reduces serum total cholesterol levels in a rat model of diet-induced hypercholesterolemia at 0.2% w/w; suppresses benzo(a)pyrene-induced forestomach tumor formation in mice
Cayman Chemical p-CoumarIc AcId 10g
A hydroxy derivative of cinnamic acid that can be found in a variety of edible plants that is reported to have antioxidant, anti-inflammatory, and antimicrobial activity
Cayman Chemical p-CoumarIc AcId 250g
A hydroxy derivative of cinnamic acid that can be found in a variety of edible plants that is reported to have antioxidant, anti-inflammatory, and antimicrobial activity
Medchemexpress LLC Entacapone | 130929-57-6 | MFCD00866580 | >98.0% | 305.29 g/mol | C14H15N3O5 | 5 MG
Entacapone is a research-grade catechol-O-methyltransferase (COMT) inhibitor supplied as a small-scale reagent. It is potent, reversible, peripherally acting, and orally active, and is used in Parkinson's disease research and studies of FTO demethylation.
- Potent, reversible COMT inhibitor.
- Peripherally acting and orally active.
- Suitable for Parkinson's disease research.
- Inhibits FTO demethylation for metabolic research.
- Purity >98.0% (HPLC) reported by suppliers.
- Molecular formula C14H15N3O5; molecular weight 305.29 g/mol.
- Supplied as a small-scale research pack (5 mg).
![eMolecules 176776-60-6 | 2,2'-(1E,1'E)-(TRANS (+/-)-CYCLOHEXANE-1,2- DIYLBIS(AZAN-1-YL-1-YLIDENE)BIS(METHAN-1-YL-1-YLIDENE)DIPHENOL | AstaTech644.816 | C40H44N4O4 | 95.000 | Oc1ccccc1\C=N\[C@@H]1CCCC[C@H]1\N=C\c1ccccc1O.Oc1ccccc1\C=N\[C@H]1CCCC[C@@H]1\N=C\c1ccccc1O | 1g | 112531835](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502171610.JPG-250.jpg)
eMolecules 176776-60-6 | 2,2'-(1E,1'E)-(TRANS (+/-)-CYCLOHEXANE-1,2- DIYLBIS(AZAN-1-YL-1-YLIDENE)BIS(METHAN-1-YL-1-YLIDENE)DIPHENOL | AstaTech644.816 | C40H44N4O4 | 95.000 | Oc1ccccc1\C=N\[C@@H]1CCCC[C@H]1\N=C\c1ccccc1O.Oc1ccccc1\C=N\[C@H]1CCCC[C@@H]1\N=C\c1ccccc1O | 1g | 112531835
2,2'-(1E,1'E)-(TRANS (+/-)-CYCLOHEXANE-1,2- DIYLBIS(AZAN-1-YL-1-YLIDENE)BIS(METHAN-1-YL-1-YLIDENE)DIPHENOL | AstaTech | 176776-60-6644.816 | C40H44N4O4 | 95.000 | Oc1ccccc1\C=N\[C@@H]1CCCC[C@H]1\N=C\c1ccccc1O.Oc1ccccc1\C=N\[C@H]1CCCC[C@@H]1\N=C\c1ccccc1O | 1g | 112531835
Accela Chembio Inc 2-methylcinnamic Acid | Predominantly Trans | 25g | 2373-76-4 | MFCD00016841 | 97+% | Shelf Life: 1260 Days | Light Sensitive
2-methylcinnamic Acid | Predominantly Trans | 25g | 2373-76-4 | MFCD00016841 | 97+% | Shelf Life: 1260 Days | Light Sensitive
Selleck Chemical LLC Bisdemethoxycurcumin (BDMC) S3938-25mg
Bisdemethoxycurcumin (BDMC) is a natural demethoxy derivative of curcumin and possesses several biological activities such as anti-inflammation and anti-cancer activities
Apexbio Technology LLC Tyrphostin A1 2826-26-8 10mg
Tyrphostin A1 (CAS 2826-26-8) is a small molecule inhibitor targeting tyrosine kinase activity specifically involved in disrupting intracellular signaling pathways in immune cells It has been shown to interfere with CD40 ligand-induced signaling resulting in suppressed interleukin-12 (IL-12) secretion by macrophages and reduced differentiation of antigen-induced T helper 1 (Th1) cells Tyrphostin A1 is widely utilized in studies investigating cell-to-cell signaling immune response modulation and the mechanisms underlying inflammatory processes particularly in the context of autoimmune disease models
Medchemexpress LLC 4-Methoxycinnamic acid | 830-09-1 | 178.19 | 25 G
4-Methoxycinnamic acid is detected as a natural phenylpropanoid in A. preissii. For optimal preservation, store the powder at -20°C for up to 3 years or 4°C for up to 2 years. If in solvent, store at -80°C for 2 years or -20°C for 1 year. Keep the container tightly sealed in a cool, well-ventilated area, away from direct sunlight and sources of ignition. Shipping is at room temperature if the duration is less than 2 weeks.
- Endogenous metabolite
- Structure classification: Ketones, aldehydes, acids
- Initial source: Endogenous metabolite
- Purity: 99.87%